The leading point-of-care wound imaging devices
for the detection of the presence and location of
elevated bacterial loads and for accurate digital
wound measurement.
MolecuLight i:X
Arthrex is the global market leader for PRP / PRF systems and has been distributing its high-quality medical products in various fields for more than 10 years, including aesthetic medicine, dermatology, orthopaedics and plastic surgery.
Other innovative products and techniques, such as the ACA technique for harvesting microfat and stromal-vascular fraction (SVF) and unique training programs, help Arthrex to achieve its mission of Helping Surgeons Treat Their Patients Better®.
MolecuLight i:X
Wound Imaging Device
The MolecuLight i:X allows clinicians to quickly, safely and easily visualize bacteria and measure wounds at the point of care.
Focused
Allows clinicians to focus on harmful bacteria with the guidance of fluorescence imaging
Efficient
Immediately know where to sample, where to debride and/or if you need an expensive antimicrobial product.
No Contact
No contrast agents and no patient contact required.
Point-of-Care
Instantly detects and reveals location of potentially harmful levels of bacteria. Wound area is also easily calculated on the i:X
Precise
Allows for more targeted treatment protocols by knowing exactly where fluorescent bacteria are.
Ease of Use
Portable, touch-screen with an intuitive interface.
What does MolecuLight i:X do?
Frequently Asked Questions
In a darkened room, or using a DarkDrape™, the MolecuLighti:Xshines a safe violet excitation light (405 nm) on a wound. This causes wound components (skin, slough, blood, bacteria, etc.) to fluoresce (or emit light) in different colours1–4.The i:X device displays and captures images of the most informative of these fluorescent colours. Green fluorescence from skin components (i.e. collagen and fibrin) provides anatomical context. Red and cyan fluorescence are associated with regions of bacterial at loads of >104 CFU/g1–3, which is typically moderate-to heavy growth1–3, as demonstrated in multiple clinical studies. Bacterial loads of less than 104 CFU/g, such as the loads of commensal bacteria on healthy skin, are not detected by the MolecuLight i:X1,4.
In addition to bacterial detection, the i:X also performs digital wound area measurement to document and longitudinally monitor the progress of wounds.
Pre-clinical and clinical studies have shown that the MolecuLighti:X can detect red fluorescence from Gram positive, Gram negative, aerobic and anaerobic bacterial species, , whether they are planktonic or in a biofilm1,5.
Pre-clinical research has demonstrated the following species can produce red fluorescence detectable by the MolecuLight i:X in vitro5 (see list below). However, there are many bacterial species not tested here that may also produce red fluorescence6.
Gram negative aerobic species
- Pseudomonas aeruginosa
- Escherichia coli
- Proteus mirabilis
- Proteus vulgaris
- Enterobacter cloacae
- Serratia marcescens
- Acinetobacter baumannii
- Klebsiella pneumoniae
- Klebsiella oxytoca
- Morganella morganii
- Stenotrophomonas maltophilia
- Citrobacter koseri
- Citrobacter freundii
- Aeromonas hydrophilia
- Alcaligenes faecalis
- Pseudomonas putida
Gram positive aerobic species
- Staphylococcus aureus
- Staphylococcus epidermis
- Staphlyoccus lugdunensis
- Staphylococcus capitis
- Corynebacterium striatum
- Bacillus cereus
- Listeria monocytogenes
Anaerobic species
- Bacteroides fragilis
- Clostridium perfringens
- Peptostreptococcus anaerobius
- Propionibacterium acnes
- Veillonella parvula
The MolecuLighti:X can be used at the point-of-care to help wound care practitioners optimize all wound protocols including improved accuracy of sampling7,8, more effective wound cleaning and debridement9–11, as well as helping with dressing and antimicrobial selection4,12. Not only can the i:X help optimize these protocols, it also assists in tracking the effectiveness of treatment plan decreasing bacterial load and wound size9,13. This allows the practitioner to modify the treatment plan if the patient is not responding to the current treatment plan9,13.
Ultimately, this leads in to increased 12-week healings rates, as shown in multiple RCT and retrospective studies14,15
The MolecuLight i:X device is straight-forward to learn and operate. The device’s user interface is designed to be intuitive and easy to use, without requiring a technical background. The device is hand-held and does not require any contrast agents.
NuAngle Medical provides comprehensive on-site training for all staff and there is a library of online e-learning modules, online assessments, and videos to assist all wound care practitioners with image interpretati
In order to detect bacteria, fluorescence imaging using the MolecuLight i:X requires a dark room. Darkness is required so that fluorescence signals emitted from the bacteria (and other biological components) in a wound are clearly visualized by the device. In order to ensure a room is sufficiently dark, the i:X has an ambient light sensor to inform the user if the room is dark enough.
If a clinical room can’t be darkened (e.g. an open ward or a treatment room with large windows), a DarkDrape® is available as a disposable, portable dark environment to provide the required darkness for successful point-of-care fluorescence imaging.
Insufficient darkness may lead to images that are not able to be accurately interpreted.